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Menstrual Migraine: Why It Hits Around Your Period, What Helps, and When to See a Doctor

Migraine that clusters around your period — usually days −2 to +3 — driven by the late-luteal estrogen drop, and what tracking can add.

Jane Smorodnikova
Founder & CEO
Kseniia Iaroslavtseva
COO & Strategy team teamlead
Anna Elitzur
Medical Advisor
A menstrual migraine is a migraine attack that keeps landing in a predictable period window, usually from 2 days before bleeding through about 3 days after it starts. The classic trigger is not the bleeding but the late-luteal drop in estrogen, which can lower the brain's migraine threshold. Doctors separate pure menstrual migraine (attacks only around the period) from the more common menstrually related migraine (period attacks plus attacks at other times). Perimenstrual attacks tend to last longer and recur more. Among 396 Welltory users who self-report migraine, the clearest separator from other users was self-reported brain fog (49% vs 25%), while a single wearable reading like HRV did not cleanly set the groups apart — so a cycle-and-symptom diary, not one morning number, is what makes the pattern legible for you and your clinician.

Short Answer

A menstrual migraine is a migraine attack that keeps showing up in a predictable period window: usually from 2 days before bleeding starts through about 3 days after it starts. In headache criteria, that window is often written as days −2 to +3, with day 1 being the first day of menstruation. The classic trigger is not the bleeding itself; it is the late-luteal drop in estrogen, which can lower your brain's migraine threshold just as your period is about to begin. The estrogen-withdrawal idea goes back to Somerville's experimental work and is still the main working model, although newer reviews note that the biology is more complex than one hormone falling in isolation. (nice.org.uk)

Doctors usually separate two patterns. Pure menstrual migraine means attacks happen only in that perimenstrual window. Menstrually related migraine means you get attacks around your period and at other times in the cycle. The menstrually related pattern is the more common of the two, while a truly "pure" menstrual pattern is comparatively rare and needs cycle-by-cycle confirmation to establish. Perimenstrual attacks can be longer, more severe, and more relapse-prone than attacks outside the period window, which is why they often feel like your "usual migraine, but harder to stop." (pmc.ncbi.nlm.nih.gov)

Around perimenopause, the pattern may change again because estrogen and progesterone become less predictable. Some people get more frequent or less predictable attacks during this transition, especially if they already have menstrual migraine. That does not mean hormones are the only lever; sleep, stress load, missed meals, dehydration, pain sensitivity, and medication timing can all stack on top of the cycle signal. (pubmed.ncbi.nlm.nih.gov)

What helps starts with a diary: track bleeding days, migraine days, aura symptoms, sleep, stress, and medication use for at least 2 menstrual cycles so you and your clinician can see whether the pattern is truly menstrual. From there, care can include acute migraine treatment, anti-nausea support if needed, and — when attacks are predictable and standard acute treatment is not enough — short-term prevention taken on the days migraine is expected. NICE notes that a clinician may offer period-timed preventive triptan treatment for menstrually related migraine, and also says people with migraine with aura should not usually be offered the combined contraceptive pill. Any medication, hormonal option, or prevention plan should be chosen with a clinician who knows your migraine type, aura history, pregnancy plans, cardiovascular risk, and other conditions. (nice.org.uk)

What our data shows — the felt burden, and why a cycle diary beats a single reading

Among 396 Welltory users who self-report migraine, compared with 3,749 users who do not, one pattern separated the groups clearly: self-reported brain fog. About 49% of the migraine group flagged brain fog, versus 25% of everyone else — a gap that held up even when we compared people carrying the same number of other conditions, so it tracks with migraine itself rather than simply with a heavier overall health load. The "hard" wearable numbers separated people far less: the morning HRV score was essentially identical between groups (3.11 vs 3.11), and resting heart rate ran only modestly higher (65.5 vs 62.5 bpm) in a way that flattened out on like-for-like comparison.

The practical takeaway for menstrual migraine: a single morning reading is too blunt to carry the whole signal. What tends to be useful is your own pattern over time — and, for cycle-linked attacks, the combination of a cycle log with sleep, stress, and HRV context. Estrogen and autonomic tone move together across the cycle, so tracking the run-up to your period can help you (and your clinician) see when your nervous system may be more reactive. That is a qualitative angle, not a prediction: our cohort does not measure per-cycle attack timing, so we can't put a number on a "vulnerable window" from our data — we can only say the felt burden is real and that a diary makes it legible.

This is a first-party pattern from a self-identified group of Welltory users, not a clinical diagnosis, and it is not a way to diagnose or predict migraine (menstrual or otherwise). The figures are self-reported, anonymized, and aggregated; no individual user is identifiable. The reportable finding is the brain-fog gap (49% vs 25%), which held up on like-for-like comparison; the wearable numbers are shown for honesty, not as a migraine test, and we did not measure cycle-phase timing.

Menstrual migraine at a glance

Menstrual migraine is less about one "bad period" and more about a repeatable body pattern: your nervous system becomes easier to trigger in a narrow hormone-shift window, especially as estrogen falls before bleeding.

FeatureWhat it looks likeNotes
TimingAttacks cluster from about 2 days before bleeding through the first 3 days of flow.This is the standard perimenstrual window used in menstrual migraine criteria: days −2 to +3 around the first day of menstruation. If you also notice a mid-cycle or ovulation-time attack, track it, but it is not the defining menstrual migraine window. (pmc.ncbi.nlm.nih.gov)
Main triggerThe natural fall in estrogen in the late luteal / perimenstrual phase.It is the drop — not simply a high estrogen level — that matters. The classic estrogen-withdrawal studies suggested migraine can be triggered after several days of estrogen exposure when estrogen then falls; newer reviews still describe estrogen withdrawal as the leading mechanism, while noting the evidence is not perfect and individual vulnerability matters. (pubmed.ncbi.nlm.nih.gov)
Pure menstrual migraine (PMM)Migraine happens only around the period, not at other times of the cycle.PMM is less common than menstrually related migraine. In ICHD-based criteria, attacks occur only in the days −2 to +3 window in at least 2 of 3 cycles; diary studies suggest truly "pure" patterns are rare and need cycle-by-cycle confirmation. (pmc.ncbi.nlm.nih.gov)
Menstrually related migraine (MRM)Period attacks plus migraine attacks at other times of the cycle.This is the more common pattern: your period may be the most predictable trigger, but not the only one. Perimenstrual attacks also tend to last longer and recur more often than non-perimenstrual attacks in diary studies. (pmc.ncbi.nlm.nih.gov)
AuraMenstrual/perimenstrual attacks are often without aura, but aura can still happen.Aura matters for contraception safety. The CDC classifies combined hormonal contraceptives differently for migraine without aura versus migraine with aura, and lists migraine with aura as a Category 4 condition for combined hormonal contraceptives — meaning an unacceptable health risk if used. Discuss this with your doctor. (cdc.gov)
PerimenopauseAttacks can become more frequent, severe, or less predictable as cycles become irregular.During perimenopause, periods often change in timing and flow, and estrogen/progesterone patterns become more variable. That can widen the vulnerable window for some people, especially in early perimenopause, when migraine attacks may become more frequent or severe around menstruation. (nhs.uk)

The practical takeaway: if attacks keep landing in the same 5-day window, a cycle-and-migraine diary is not just "tracking." It is diagnostic evidence you can bring to a clinician, especially if you are discussing prevention, contraception, perimenopause, or a change in aura.

What a menstrual migraine is — and the two types

A menstrual migraine isn't a separate disease from migraine. It's migraine that keeps lining up with the hormonal rhythm of your menstrual cycle — most often in the vulnerable stretch around bleeding, when estrogen is falling and the brain's pain-processing system may be easier to trigger. Clinically, the menstrual window is usually counted as day 1 ± 2: the two days before bleeding starts through the first three days of the period, or days −2 to +3. In ICHD-3 research criteria, the pattern should show up in at least two out of three menstrual cycles. (pmc.ncbi.nlm.nih.gov)

These attacks tend to be migraine without aura. That doesn't mean aura can never happen around your period; it means the classic menstrual-migraine criteria and much of the research focus on attacks without aura, and perimenstrual attacks are often described as primarily non-aura attacks. (pmc.ncbi.nlm.nih.gov)

Clinicians divide the pattern into two types, and the distinction matters because it changes what you and your doctor are trying to prevent:

  • Pure menstrual migraine (PMM) — attacks happen only in the perimenstrual window and at no other time of the cycle. This is the less common pattern; diary-based studies and reviews consistently describe PMM as rare compared with menstrually related migraine, and prospective e-diary work has reported truly "pure" patterns in only a small minority of women once attacks are timed day by day. (pmc.ncbi.nlm.nih.gov)

  • Menstrually related migraine (MRM) — attacks happen around the period and at other points in the cycle. This is the more common pattern. Under ICHD-3 criteria, MRM means the attack timing meets the same days −2 to +3 menstrual-window rule, but additional migraine attacks also occur outside that window. In prospective diary studies, perimenstrual attacks also tended to involve less aura than attacks at other times of the cycle. (pmc.ncbi.nlm.nih.gov)

Because menstrual migraine is frequently underrecognized — timing is easy to miss without day-by-day records — many women live with it for years without a name for the pattern. The problem is practical: if you remember only "I get migraines," the cycle link can disappear. If you log bleeding days and headache days together, the pattern becomes visible — whether attacks are locked to the period only, or whether the period is just your highest-risk window. Prospective headache or e-diary tracking is strongly recommended in research and increasingly emphasized for clinical practice because self-reported menstrual migraine can be inaccurate without day-by-day timing. (pmc.ncbi.nlm.nih.gov)

Why it hits around your period: the estrogen drop

For many people with menstrual migraine, the main trigger is not "too much estrogen." It is the drop. Estradiol rises as you move toward ovulation, dips, rises again more modestly in the luteal phase, and then falls steeply just before bleeding starts. That late-luteal and perimenstrual withdrawal can make the migraine system more reactive: pain pathways are easier to activate, the trigeminovascular system is more sensitive, and your usual triggers — poor sleep, stress, skipped meals, alcohol, hard workouts — may hit harder than they would at another point in the month. This estrogen-withdrawal model goes back to Somerville's experimental work and is still the most commonly used explanation for why attacks cluster around menstruation, although researchers continue to study the exact mechanism. (pmc.ncbi.nlm.nih.gov)

That same pattern shows up in hormone-tracking research. Women with migraine have been found to have a faster late-luteal decline in estrogen metabolites than women without migraine, even when average hormone levels are not dramatically different across the whole cycle. In plain English: the problem may be less about your "baseline estrogen" and more about how fast your nervous system has to adapt when estrogen falls. (pubmed.ncbi.nlm.nih.gov)

This fits a broader menstrual-cycle pattern, too. The high-estradiol peri-ovulatory phase is often described as a more resilient window, while the late luteal and perimenstrual window can be a more vulnerable one — not just for headache, but for stress sensitivity and other symptoms in some people. As one cycle study describes it, the high-estradiol peri-ovulatory phase acts as a window of resilience, and the luteal phase — with its changing progesterone levels — as a window of vulnerability to stress-related symptoms. (pubmed.ncbi.nlm.nih.gov)

The practical takeaway: your migraine risk is not random across the month. It often concentrates in a predictable window — the days before bleeding and the first days of your period — and that window is something you can learn to see in your own cycle data.

Seeing your vulnerable window: what tracking adds

You can't diagnose menstrual migraine from a wearable. But you can turn a vague "I always get headaches around my period" into a dated, repeatable pattern a clinician can use. Start with the basics: log cycle day + attack timing + severity + aura yes/no for at least two cycles, and ideally across three. NICE recommends a headache diary for diagnosing menstrually related migraine, and the ICHD-based criteria look for attacks that cluster from 2 days before to 3 days after bleeding starts in at least 2 out of 3 menstrual cycles. That timing helps separate a pure menstrual pattern — attacks only in the perimenstrual window — from a menstrually related pattern, where period-linked attacks happen alongside attacks at other times. (nice.org.uk)

Two physiological layers make this richer than a paper diary. First, estrogen and autonomic tone move together across the cycle — as vagal tone shifts with hormonal changes through the month. Because HRV reflects autonomic regulation, an HRV and resting-heart-rate log may show your body's run-up into the vulnerable window — not as a diagnosis, but as context around the attack: lower recovery, higher strain, a different baseline than your usual. Research linking menstrual-cycle phase, ovarian hormone shifts, and autonomic measures also notes that cycle phase should be interpreted cautiously, because people vary. (pmc.ncbi.nlm.nih.gov)

Second, sleep belongs in the same chart. Too little sleep, too much sleep, or a disrupted sleep schedule can trigger migraine for some people, and menstrual migraine often lands in a window where fatigue, cramps, mood shifts, and pain can already disturb rest. If your period week shows shorter sleep, more wake-ups, lower HRV, and then migraine, that sequence is useful. It tells your clinician what tends to come first — the sleep disruption, the autonomic dip, the bleeding, the aura, the pain — instead of leaving you to explain it from memory. (medlineplus.gov)

The point isn't self-diagnosis. It's arriving at the appointment with a chart that says: "Here is my window. Here is what precedes it. Here is whether aura happens. Here is how severe it gets." That is the difference between "maybe it's just hormones" and a management conversation about timing, prevention, safety, and what to do before the attack fully takes over.

What helps

Menstrual migraine is treated in layers, and the specifics of any medication — which drug, what dose, what schedule — are a decision for you and your doctor, not a self-serve menu. Below is the shape of the options, class-level only, with no doses by design. NICE separates care into acute migraine treatment, preventive treatment, and a specific short-term option for predictable menstrually related migraine when standard acute treatment is not enough; reviews of menstrual migraine management describe the same layered approach: treat the attack, then consider short-window prevention or hormonal strategies when the pattern is predictable and disabling. (nice.org.uk)

Track first, then target. Because the window is predictable, both you and your clinician can plan around it. A headache diary helps show whether attacks cluster around the cycle, how long they last, what you took, and whether a plan is working; NICE specifically recommends diagnosing menstrually related migraine with a diary across at least 2 menstrual cycles. Consistent sleep, hydration, regular meals, physical activity, and stress management across the vulnerable days are the low-risk foundation everyone can start with, because missed sleep, skipped meals, dehydration, and stress can lower the threshold for a migraine attack when your nervous system is already more sensitive. (nice.org.uk)

Acute treatment — taken when an attack starts. This is the same family of options used for migraine generally: nonprescription pain relievers or NSAIDs for some people, and prescription migraine-specific acute drugs such as triptans for others. Which acute drug is appropriate, and whether a migraine-specific prescription option fits you, is a medical decision — some are unsuitable in certain people, and your doctor weighs your full history, other conditions, pregnancy status, medication interactions, and the risk of medication-overuse headache. (nice.org.uk)

Short-term ("mini") prevention — because the trigger window is predictable, clinicians sometimes use a preventive taken only around the period rather than every day. This is usually considered when attacks are predictable and standard acute treatment is not enough; NICE names short-term triptan-based prevention as an option for predictable menstrually related migraine that has not responded adequately to acute treatment. Mini-prophylaxis is a doctor-directed strategy: the choice of agent, timing, and whether it's appropriate at all depends on your pattern and history — it is not something to self-start. (nice.org.uk)

Hormonal approaches — because the trigger is often the estrogen drop, some strategies aim to smooth that fall. For some people, a clinician may consider changing a contraceptive pattern or using a hormone-based approach; for others, hormones can worsen migraine or add risk. Hormonal management of menstrual migraine is entirely a clinician's decision; it can help some women and is inappropriate or risky for others, and it interacts with the aura question below. Combined hormonal contraception is not routinely offered for people with migraine with aura in NICE guidance, and the CDC classifies combined hormonal contraception differently for migraine without aura versus migraine with aura. This is a conversation to have with your doctor. (my.clevelandclinic.org)

Supplements and "natural" routes are among the most-searched angles — especially magnesium, riboflavin, and CoQ10. The evidence is uneven: riboflavin is mentioned in NICE guidance for migraine prevention in some people, while magnesium has small menstrual-migraine-specific trial data and broader migraine-prevention evidence, but study size, supplement form, and results vary. "Natural" is not the same as "risk-free" or "proven," and supplements can still cause side effects or interact with medication, so discuss any supplement with your clinician, especially if you are pregnant, trying to conceive, taking migraine prescriptions, or taking other daily medications. (nccih.nih.gov)

The aura + estrogen-contraception safety point (talk to your doctor)

This is the one safety fact worth spelling out because aura changes the contraception conversation. Menstrual migraine is classified under migraine without aura in the CDC contraception guidance, but if your attacks include aura — visual changes, tingling or numbness, speech trouble, or other reversible neurologic symptoms — that detail matters. For migraine with aura, combined hormonal contraception, meaning estrogen-containing methods such as combined pills, patches, or rings, is treated as a higher-safety-risk option because both aura and estrogen exposure can push ischemic-stroke risk in the wrong direction. The CDC's 2024 U.S. Medical Eligibility Criteria lists combined hormonal contraception as Category 4 for migraine with aura — a category defined as an unacceptable health risk if the method is used. (cdc.gov)

Reviews of contraceptive cardiovascular safety add useful context. Estrogen-containing combined hormonal contraceptives raise the relative risk of venous thromboembolism, though among healthy young nonsmokers the absolute event rates stay low; the risk is strongly modified by estrogen dose, progestin type, route of administration, and individual factors such as age, smoking, migraine with aura, and high blood pressure. The same literature notes that progestin-only methods and levonorgestrel-releasing IUDs generally show a more favorable clotting profile and are often preferred when estrogen is contraindicated. (pubmed.ncbi.nlm.nih.gov)

This is not a recommendation for or against any contraceptive. It means: if you have migraine with aura, the choice of contraception is a conversation to have with your doctor, who will weigh aura, smoking, blood pressure, and other factors. Do not start, stop, or switch hormonal contraception based on this article. (cdc.gov)

Knowing whether your attacks come with aura is, again, something a symptom log makes concrete. Write down what happened before the pain: sparks, zigzags, blind spots, numbness, tingling, weakness, speech changes, timing, and how long it lasted. That record helps your clinician separate "period-linked migraine" from "migraine with aura around my period" — and that is exactly the detail that can change the medical conversation. (my.clevelandclinic.org)

Menstrual migraine and perimenopause

For many women, the perimenstrual pattern shifts in perimenopause. The body is no longer running the same clean monthly rhythm: ovulation may become inconsistent, cycles may shorten or stretch, and estrogen and progesterone can swing more widely than they did earlier in reproductive life. For a migraine-prone nervous system, that can turn a familiar "right before my period" danger zone into a blurrier one — attacks may arrive earlier, cluster around bleeding, last longer, or feel harder to predict. Reviews describe perimenopause as a time when migraine frequency, severity, and predictability can worsen; after menopause, migraine often improves, but not for everyone, and migraine with aura may persist differently. (pubmed.ncbi.nlm.nih.gov)

This is one reason a woman who "handled" her menstrual migraines for years can find them suddenly worse in her 40s. It also complicates the contraception and hormone-therapy conversation: aura history, vascular risk factors, bleeding pattern, hot flashes, sleep disruption, and whether estrogen is being started, stopped, or delivered steadily all matter. If your attacks are becoming more frequent, losing their usual cycle pattern, or changing alongside perimenopause symptoms, it's worth raising this specifically with a clinician. (pubmed.ncbi.nlm.nih.gov)

When to see a doctor

See a clinician if your attacks reliably cluster before or during your period and are stealing workdays, sleep, parenting, exercise, or normal life — that pattern can be menstrual migraine, and it often responds better when your doctor can plan treatment around the cycle rather than chase each attack after it starts. Also book a visit if over-the-counter options are not controlling the pain, your headaches are becoming more frequent or severe, or the timing, quality, or symptoms suddenly feel different from your usual migraine. Hormone shifts in perimenopause can make migraine more frequent or painful for some people, but a new or changing pattern still deserves a medical review instead of being written off as "just hormones." (my.clevelandclinic.org)

Be especially careful with hormonal contraception. If you have migraine and are considering birth control — or you already use it and develop migraine, aura, or a new headache pattern — bring this up with a clinician before changing anything yourself. This matters most with migraine with aura, because the CDC classifies combined hormonal contraception — pills, patch, or ring with estrogen — as not recommended for people with migraine with aura, and it notes that new headaches or marked headache changes should be evaluated. (cdc.gov)

Get prompt medical evaluation — urgent care or emergency care, depending on severity — for any new, sudden, "worst-ever," thunderclap-type headache, or for headache with aura-like or stroke-like symptoms such as weakness, numbness, trouble speaking, confusion, fainting, seizures, stiff neck, fever, double vision, vision loss, or trouble walking. Even if you usually get migraine, those symptoms can overlap with other conditions that need fast assessment. (medlineplus.gov)

Bring your cycle-and-symptom log. Track bleeding days, headache days, pain severity, aura or neurological symptoms, nausea, light/sound sensitivity, sleep, stress, medications, and what helped. A prospective diary can show whether attacks repeatedly fall in the menstrual window and can make the appointment faster, more specific, and more useful. (pmc.ncbi.nlm.nih.gov)

How we made it

This page was drafted with AI tools, then edited, fact-checked, and medically reviewed by the Welltory team. Medical claims were checked against authoritative migraine and contraception references, including NICE clinical guideline CG150, the CDC 2024 U.S. Medical Eligibility Criteria for Contraceptive Use, MedlinePlus, Cleveland Clinic, and recent peer-reviewed studies on menstrual migraine timing, estrogen withdrawal, the autonomic nervous system, and perimenopause.

The cohort figures on this page come from a self-identified group of Welltory users, not from clinically diagnosed patients. All figures are reported as anonymized, aggregated data; no individual user is identifiable. They describe patterns in our app data — not a way to diagnose, predict, or measure migraine for any individual person. The reportable finding is the self-reported brain-fog gap (49% vs 25%) in the broader migraine cohort, which held up when comparing people carrying the same number of other conditions; we did not measure cycle-phase attack timing, so the menstrual-window angle here is qualitative, not a quantified prediction.

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This article is for educational purposes only and does not replace diagnosis or treatment by a qualified clinician. Menstrual migraine, and any hormonal or preventive therapy for it, should be evaluated and managed by a doctor. Welltory does not diagnose or treat any condition; it helps you track patterns to bring to your clinician.

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Written by Jane Smorodnikova

The founder and CEO of Welltory. A recognized tech leader with two Master's degrees and experience at MIT, she has scaled Welltory to over 17 million users.

Written by Kseniia Iaroslavtseva

She reviews scientific research and turns it into structured, readable insights.

Reviewed by Anna Elitzur

With her medical degree, Anna reviews Welltory's health content for medical accuracy and alignment with current clinical guidelines and research.

References

  1. Verhagen I. E., Spaink H. A. J., van der Arend B. W. H., van Casteren D. S., MaassenVanDenBrink A., Terwindt G. M. (2022). Validation of diagnostic ICHD-3 criteria for menstrual migraine. Cephalalgia, 42(11–12), 1184–1193. DOI 10.1177/03331024221099031. https://pubmed.ncbi.nlm.nih.gov/35514214/
  2. van Casteren D. S., Verhagen I. E., van der Arend B. W. H., van Zwet E. W., MaassenVanDenBrink A., Terwindt G. M. (2021). Comparing Perimenstrual and Nonperimenstrual Migraine Attacks Using an e-Diary. Neurology, 97(17), e1661–e1671. DOI 10.1212/WNL.0000000000012723. https://pmc.ncbi.nlm.nih.gov/articles/PMC8605615/
  3. Somerville B. W. (1975). Estrogen-withdrawal migraine. I. Duration of exposure required and attempted prophylaxis by premenstrual estrogen administration. Neurology, 25(3), 239–244. DOI 10.1212/WNL.25.3.239. https://pubmed.ncbi.nlm.nih.gov/1167630/
  4. Raffaelli B., Do T. P., Chaudhry B. A., Ashina M., Amin F. M., Ashina H. (2023). Menstrual migraine is caused by estrogen withdrawal: revisiting the evidence. The Journal of Headache and Pain, 24, 131. DOI 10.1186/s10194-023-01664-4. https://pubmed.ncbi.nlm.nih.gov/37730536/
  5. Pavlović J. M., Allshouse A. A., Santoro N. F., Crawford S. L., Thurston R. C., Neal-Perry G. S., Lipton R. B., Derby C. A. (2016). Sex hormones in women with and without migraine: Evidence of migraine-specific hormone profiles. Neurology, 87(1), 49–56. DOI 10.1212/WNL.0000000000002798. https://pubmed.ncbi.nlm.nih.gov/27251885/
  6. NICE. (2012; updated 2025). Headaches in over 12s: diagnosis and management. Clinical guideline CG150. https://www.nice.org.uk/guidance/cg150/chapter/recommendations
  7. CDC. (2024). U.S. Medical Eligibility Criteria for Contraceptive Use, 2024 — Appendix D: Classifications for Combined Hormonal Contraceptives. https://www.cdc.gov/contraception/hcp/usmec/combined-hormonal-contraceptives.html
  8. CDC. (2024). U.S. Medical Eligibility Criteria for Contraceptive Use, 2024 — Appendix A: Summary of Classifications. https://www.cdc.gov/contraception/hcp/usspr/classifications-mec-contraception.html
  9. Ornello R., De Matteis E., Di Felice C., Caponnetto V., Pistoia F., Sacco S. (2021). Acute and Preventive Management of Migraine during Menstruation and Menopause. Journal of Clinical Medicine, 10(11), 2263. DOI 10.3390/jcm10112263. https://pubmed.ncbi.nlm.nih.gov/34073696/
  10. Friedman Korn T., Bernstein C. (2026). Migraine across the menopausal transition and beyond: A narrative review. Headache, 66(6), 1390–1404. DOI 10.1111/head.70071. https://pubmed.ncbi.nlm.nih.gov/41934093/
  11. Pletzer B., Hausinger T., Thoms N., Gierg C., Beltz A. M. (2026). Menstrual cycle variations in stress vulnerability and sociability relate to mental health symptoms and libido. npj Women's Health, 4, 18. DOI 10.1038/s44294-026-00140-z. https://pubmed.ncbi.nlm.nih.gov/42004752/
  12. Gozansky E., Okon-Singer H., Weissman-Fogel I. (2026). Baseline vagal tone and pain reactivity: linking autonomic function to endogenous pain inhibition in women. Pain Reports, 11(2), e1390. DOI 10.1097/PR9.0000000000001390. https://pubmed.ncbi.nlm.nih.gov/41675412/
  13. Waluszewska I., Borowiec A., Paciorek A., Musz L., Szczurek-Wasilewicz W. (2026). Cardiovascular Safety of Hormonal Contraception: Method-Specific Risks and Clinical Implications. Medical Sciences, 14(2), 201. DOI 10.3390/medsci14020201. https://pubmed.ncbi.nlm.nih.gov/42029625/
  14. Facchinetti F., Sances G., Borella P., Genazzani A. R., Nappi G. (1991). Magnesium prophylaxis of menstrual migraine: effects on intracellular magnesium. Headache, 31(5), 298–301. DOI 10.1111/j.1526-4610.1991.hed3105298.x. https://pubmed.ncbi.nlm.nih.gov/1860787/
  15. MedlinePlus. (updated 2026). Migraine. https://medlineplus.gov/migraine.html
  16. NCCIH. Headaches and Complementary Health Approaches: What the Science Says. https://www.nccih.nih.gov/health/providers/digest/headaches-and-complementary-health-approaches-science